Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49771 | 1.00 | — | — | |
| SCHEMBL10597462 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| Phosphoric Acid SCHEMBL16447462 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL10598792 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| SCHEMBL1677255 | 0.97 | — | — | |
| SCHEMBL6246557 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| SCHEMBL6246227 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| Ammonia Solution, Strong SCHEMBL11578534 | 0.97 | — | — | |
| SCHEMBL5313172 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 | |
| SCHEMBL6246965 | 0.97 | CA4 (0.48) | CA4PEPDALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189772-B | Phosphoketolase and phosphate transacetylase produce acetyl-coacetylase derivative compound purposes | 阿迈瑞斯公司 | 2019-09-13 | — | — | CN | disclosed |
| EP-3080243-B1 | USE OF ENZYMES WHICH CATALYZE PYRUVATE SYNTHESIS FROM FORMATE AND ACETYL-COA AND BACTERIA EXPRESSING SAME | YEDA RES & DEV (IL) | 2018-09-05 | — | — | EP | disclosed |
| US-10053712-B2 | Use of enzymes which catalyze pyruvate synthesis from formate and acetyl-CoA and bacteria expressing same | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2018-08-21 | — | — | US | disclosed |
| US-20170081682-A1 | USE OF ENZYMES WHICH CATALYZE PYRUVATE SYNTHESIS FROM FORMATE AND ACETYL-COA AND BACTERIA EXPRESSING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-03-23 | — | — | US | disclosed |
| EP-3080243-A1 | USE OF ENZYMES WHICH CATALYZE PYRUVATE SYNTHESIS FROM FORMATE AND ACETYL-COA AND BACTERIA EXPRESSING SAME | Yeda Research and Development Co., Ltd. (IL) | 2016-10-19 | — | — | EP | disclosed |
| CN-105189772-A | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds | AMYRIS INC | 2015-12-23 | — | — | CN | disclosed |
| WO-2015087327-A1 | USE OF ENZYMES WHICH CATALYZE PYRUVATE SYNTHESIS FROM FORMATE AND ACETYL-COA AND BACTERIA EXPRESSING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-06-18 | — | — | WO | disclosed |