Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029236 | 0.86 | HRH4 (0.56) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL30310376 | 0.81 | FLT3 (0.58) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL970309 | 0.81 | RHEB (0.62) | FLT3HRH4DAOALDH1A1LMNA | |
| SCHEMBL24020360 | 0.81 | FLT3 (0.58) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL29414287 | 0.81 | RHEB (0.62) | FLT3HRH4DAOALDH1A1LMNA | |
| SCHEMBL21200622 | 0.80 | FLT3 (0.57) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL29867215 | 0.80 | FLT3 (0.57) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL24112430 | 0.80 | HRH4 (0.59) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL20505087 | 0.80 | FLT3 (0.57) | FLT3HRH4DAOHDAC3HDAC1 | |
| SCHEMBL31392771 | 0.79 | KDM4E (0.58) | FLT3HRH4DAOHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087094-A1 | NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SEMMELWEIS EGYETEM (HU) | 2015-06-18 | — | — | WO | disclosed |