Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177961 | 0.87 | ITGAL (0.30) | ITGALCRBNDDB1 | |
| SCHEMBL6113104 | 0.85 | SCD (0.33) | ITGALCRBNDDB1 | |
| SCHEMBL168874 | 0.85 | ITGAL (0.45) | ITGALCRBNDDB1NPC1RAB9A | |
| SCHEMBL166858 | 0.85 | ITGAL (0.39) | ITGALCRBNDDB1NPC1RAB9A | |
| SCHEMBL168799 | 0.83 | ITGAL (0.35) | ITGALNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6113318 | 0.82 | ITGAL (0.39) | ITGALCRBNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6112955 | 0.80 | TSHR (0.35) | ITGALNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8406404 | 0.80 | MAPT (0.35) | ITGALMAPT | |
| SCHEMBL2857196 | 0.80 | CRBN (0.31) | CRBNDDB1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6113075 | 0.80 | ITGAL (0.38) | ITGALNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-24 | — | — | US | disclosed |
| EP-2424838-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer CropScience AG (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124845-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | WO | disclosed |
| WO-2010124845-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129854-A1 | Pesticidal Arylpyrrolidines | DDT, AADAC, AHR | ITGAL 3507/4885CRBN 2617/4885DDB1 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.