⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3989087 | 1.00 | — | — | |
| SCHEMBL5696389 | 1.00 | — | — | |
| SCHEMBL12267693 | 0.86 | — | — | |
| SCHEMBL11065476 | 0.84 | — | — | |
| SCHEMBL11065473 | 0.84 | — | — | |
| SCHEMBL2992683 | 0.81 | — | — | |
| SCHEMBL2992678 | 0.81 | — | — | |
| SCHEMBL23852595 | 0.78 | — | — | |
| SCHEMBL762121 | 0.78 | — | — | |
| SCHEMBL16993637 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12516009-B2 | Sustainable process for the manufacture of 1,1,4,4-tetramethoxy-2-butene | DSM IP ASSETS B.V. (NL) | 2026-01-06 | — | — | US | claimed |
| US-20230144339-A1 | SUSTAINABLE PROCESS FOR THE MANUFACTURE OF 1,1,4,4-TETRAMETHOXY-2-BUTENE | DSM IP ASSETS B.V. (NL) | 2023-05-11 | — | — | US | claimed |
| EP-4110749-A1 | SUSTAINABLE PROCESS FOR THE MANUFACTURE OF 1,1,4,4-TETRAMETHOXY-2-BUTENE | DSM IP Assets B.V. (NL) | 2023-01-04 | — | — | EP | claimed |
| CN-115135630-A | Sustainable process for the manufacture of 1,1,4, 4-tetramethoxy-2-butene | 帝斯曼知识产权资产管理有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-112125789-B | Preparation method of 1, 8-alkoxy-1, 3,6, 8-tetramethoxy-2, 7-dimethyl-4-octene | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-111943819-B | Method for preparing deca-dialdehyde intermediate | 万华化学集团股份有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-112121859-B | Catalyst and preparation method thereof, and preparation method of 1,1,4, 4-tetramethoxy-2-butene | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-110563561-B | Preparation method of 1,1,4, 4-tetramethoxy-2-butene | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-114214648-A | Electrochemical synthesis method for preparing 1,1,4, 4-tetramethoxy-2-butene | 万华化学集团股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-114044735-A | Method for synthesizing tetra-acetal | 万华化学集团股份有限公司 | 2022-02-15 | — | — | CN | claimed |
| EP-1099676-B1 | Process for the preparation of 1,1,4,4-tetramethoxybutene-2 | BASF AG (DE) | 2003-10-29 | — | — | EP | claimed |
| CN-1099911-C | Use of hydrogen-bis (oxalato) borate | HOFFMANN LA ROCHE (CH) | 2003-01-29 | — | — | CN | claimed |
| US-20020128520-A1 | Preparation of 1,1,4,4 - tetramethoxy-2-butene | WEGNER CHRISTOPH (DE) | 2002-09-12 | — | — | US | claimed |
| US-6407291-B1 | REACTING 2,5-DIMETHOXYFURAN WITH METHANOL IN PRESENCE OF SOLID ZEOLITE CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | claimed |
| US-5886196-A | Method of catalyzing condensation reactions | ROCHE VITAMINS INC. (US) | 1999-03-23 | — | — | US | claimed |
| EP-0581097-B1 | Process for the preparation of E,Z-butenedial bis-dialkyl acetals | BASF AG (DE) | 1998-11-25 | — | — | EP | claimed |
| CN-1161251-A | Use of hydrogen-bis (oxalato) borate | HOFFMANN LA ROCHE (CH) | 1997-10-08 | — | — | CN | claimed |
| EP-0784042-A1 | Use of hydrogen bis(oxalato)borate | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | claimed |
| US-5386063-A | Forming a synthetic carotenoids chemical intermediates by reacting triethyl-2-phosphonopropionate with fumarylaldehyde and/or fumarylaldehyde dimethylacetal containing carbon isotope | THE CATHOLIC UNIVERSITY OF AMERICA (US) | 1995-01-31 | — | — | US | claimed |
| EP-0581097-A1 | Process for the preparation of E,Z-butenedial bis-dialkyl acetals | BASF Aktiengesellschaft (DE) | 1994-02-02 | — | — | EP | claimed |