Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276942 | 1.00 | KMT2A (0.46) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL1147879 | 0.89 | KMT2A (0.49) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL1148009 | 0.89 | KMT2A (0.49) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL1276362 | 0.89 | KMT2A (0.43) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL31080872 | 0.87 | KMT2A (0.48) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL27133612 | 0.87 | KMT2A (0.48) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL26966046 | 0.87 | KMT2A (0.48) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL18109404 | 0.86 | KMT2A (0.47) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL15004648 | 0.86 | KMT2A (0.47) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL31080995 | 0.86 | KMT2A (0.47) | KMT2ACASP3EPHX2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303920-A2 | AMYLOID ß PEPTIDE ANALOGUES, OLIGOMERS THEREOF, PROCESSES FOR PREPARING AND COMPOSITIONS COMPRISING SAID ANALOGUES OR OLIGOMERS, AND THEIR USES | Abbott Laboratories (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2010011947-A2 | AMYLOID ß PEPTIDE ANALOGUES, OLIGOMERS THEREOF, PROCESSES FOR PREPARING AND COMPOSITIONS COMPRISING SAID ANALOGUES OR OLIGOMERS, AND THEIR USES | ABBOTT LABORATORIES (US) | 2010-01-28 | — | — | WO | disclosed |