Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 2/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097635 | 0.86 | VHL (0.55) | VHLHCAR2MLNRCYP3A4RAB9A | |
| SCHEMBL16748871 | 0.81 | VHL (0.50) | VHLHCAR2MLNRCYP3A4RAB9A | |
| SCHEMBL1698651 | 0.79 | VHL (0.58) | VHLHCAR2RAB9ANPC1MEN1 | |
| SCHEMBL6251 | 0.77 | VHL (0.60) | VHLHCAR2MEN1KMT2AEPHX2 | |
| SCHEMBL4093165 | 0.77 | VHL (0.60) | VHLHCAR2RAB9ANPC1MEN1 | |
| SCHEMBL6709129 | 0.75 | VHL (0.58) | VHLHCAR2RAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL1375734 | 0.75 | VHL (0.58) | VHLHCAR2MEN1KMT2AEPHX2 | |
| SCHEMBL314857 | 0.75 | VHL (0.58) | VHLHCAR2RAB9ANPC1MEN1 | |
| SCHEMBL4751904 | 0.75 | VHL (0.54) | VHLHCAR2RAB9AMEN1KMT2A | |
| SCHEMBL2828248 | 0.75 | VHL (0.67) | VHLHCAR2MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045271-A1 | HERBICIDALLY ACTIVE, HETEROCYCLYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-04-21 | — | — | WO | disclosed |