Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798883 | 1.00 | TSHR (0.51) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799458 | 1.00 | TSHR (0.51) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799303 | 1.00 | TSHR (0.51) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799357 | 1.00 | TSHR (0.51) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799359 | 0.98 | TSHR (0.49) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799476 | 0.87 | TSHR (0.53) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16798954 | 0.87 | TSHR (0.53) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16798989 | 0.87 | TSHR (0.53) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16798881 | 0.87 | TSHR (0.53) | TSHRALDH1A1CYP3A4SLC6A5HPGD | |
| SCHEMBL16799306 | 0.85 | TSHR (0.51) | TSHRALDH1A1CYP3A4HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077476-B1 | NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2020-02-12 | — | — | EP | disclosed |
| US-10465030-B2 | Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof | NEXDOT (FR) | 2019-11-05 | — | — | US | disclosed |
| US-20160304648-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2016-10-20 | — | — | US | disclosed |
| EP-3077476-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | Nexdot (FR) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015082656-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2015-06-11 | — | — | WO | disclosed |