Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798845 | 1.00 | TSHR (0.49) | TSHRADRA1AEPHX2KDM4EPRMT1 | |
| SCHEMBL16799490 | 1.00 | TSHR (0.49) | TSHRADRA1AEPHX2KDM4EPRMT1 | |
| SCHEMBL16799013 | 1.00 | TSHR (0.49) | TSHRADRA1AEPHX2KDM4EPRMT1 | |
| SCHEMBL16799301 | 0.98 | TSHR (0.47) | TSHRADRA1AEPHX2KDM4EPRMT1 | |
| SCHEMBL16798998 | 0.95 | TSHR (0.51) | TSHRADRA1AEPHX2KDM4EPOLB | |
| SCHEMBL22939772 | 0.94 | TSHR (0.49) | TSHRADRA1AEPHX2KDM4EPRMT1 | |
| SCHEMBL16309297 | 0.92 | TSHR (0.53) | TSHRKDM4EPOLBAPEX1HTT | |
| SCHEMBL16309329 | 0.89 | TSHR (0.58) | TSHRKDM4EPOLBAPEX1HTT | |
| SCHEMBL8438170 | 0.88 | TSHR (0.45) | TSHRADRA1AEPHX2KDM4EPOLB | |
| SCHEMBL16309326 | 0.88 | TSHR (0.53) | TSHRKDM4EPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077476-B1 | NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2020-02-12 | — | — | EP | disclosed |
| US-10465030-B2 | Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof | NEXDOT (FR) | 2019-11-05 | — | — | US | disclosed |
| US-20160304648-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2016-10-20 | — | — | US | disclosed |
| EP-3077476-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | Nexdot (FR) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015082656-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2015-06-11 | — | — | WO | disclosed |