Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.78 |
| ▸ | IKZF3 | Q9UKT9 | 7/20 | 0.78 |
| ▸ | TNF | P01375 | 5/20 | 0.78 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.78 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.78 |
| ▸ | IL1B | P01584 | 4/20 | 0.78 |
| ▸ | BRD4 | O60885 | 1/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lenalidomide SCHEMBL17999103 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL32978 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL29414335 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL30876939 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL868339 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL18825 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL10192655 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL10192650 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL10192663 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 | |
| Lenalidomide SCHEMBL29377496 | 0.88 | CRBN (1.00) | CRBNIKZF3TNFIKZF1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |
| WO-2015084905-A1 | COMBINATIONS OF HISTONE DEACETYLASE INHIBITORS AND IMMUNOMODULATORY DRUGS | ACETYLON PHARMACEUTICALS, INC. (US) | 2015-06-11 | — | — | WO | disclosed |