SCHEMBL1680179

SCHEMBL1680179

OCC=NCCN=CCO

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15962027 1.00 KDM4E (0.35) KDM4ECA12CA2
SCHEMBL9296525 0.85 KDM4E (0.33) KDM4ECA12CA2
SCHEMBL10985609 0.81
SCHEMBL872485 0.74
SCHEMBL287739 0.73 MEN1 (0.43) KDM4ECA12CA2
SCHEMBL15760047 0.73
SCHEMBL18843045 0.72
SCHEMBL13547733 0.72
SCHEMBL6680692 0.67
SCHEMBL14895032 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4796772-B2 2011-10-19 JP claimed
EP-1572773-B1 ORGANOMETALLIC-FREE POLYURETHANES HAVING LOW EXTRACTABLES LUBRIZOL ADVANCED MAT INC (US) 2008-07-09 EP claimed
EP-1572773-A1 ORGANOMETALLIC-FREE POLYURETHANES HAVING LOW EXTRACTABLES Noveon IP Holdings Corp. (US) 2005-09-14 EP claimed
WO-2004060954-A1 ORGANOMETALLIC-FREE POLYURETHANES HAVING LOW EXTRACTABLES NOVEON IP HOLDINGS CORP. (US) 2004-07-22 WO claimed
EP-3545040-B1 POLYURETHANE, METHOD OF PREPARATION, AND ARTICLE COMPRISING THE POLYURETHANE UNIV MASSACHUSETTS (US) 2023-03-15 EP disclosed
US-11046806-B2 Polyurethane, method of preparation, and article comprising the polyurethane THE UNIVERSITY OF MASSACHUSETTS (US) 2021-06-29 US disclosed
EP-3545040-A1 POLYURETHANE, METHOD OF PREPARATION, AND ARTICLE COMPRISING THE POLYURETHANE The University of Massachusetts (US) 2019-10-02 EP disclosed
US-20190256641-A1 POLYURETHANE, METHOD OF PREPARATION, AND ARTICLE COMPRISING THE POLYURETHANE THE UNIVERSITY OF MASSACHUSETTS 2019-08-22 US disclosed
WO-2018057488-A1 POLYURETHANE, METHOD OF PREPARATION, AND ARTICLE COMPRISING THE POLYURETHANE THE UNIVERSITY OF MASSACHUSETTS (US) 2018-03-29 WO disclosed
US-9804295-B2 Ophthalmic devices for sustained delivery of active compounds NOVARTIS AG (CH) 2017-10-31 US disclosed
US-20170307780-A1 OPHTHALMIC DEVICES FOR SUSTAINED DELIVERY OF ACTIVE COMPOUNDS ALCON INC. (CH) 2017-10-26 US disclosed
US-9623614-B2 Method for making contact lenses NOVARTIS AG (CH) 2017-04-18 US disclosed
US-20060251696-A1 Ophthalmic devices for sustained delivery of active compounds ALCON INC. (CH) 2006-11-09 US disclosed
EP-1697437-A2 CROSSLINKABLE POLYUREA PREPOLYMERS Novartis AG (CH) 2006-09-06 EP disclosed
WO-2006053777-A1 CROSSLINKABLE POLY(OXYALKYLENE)-CONTAINING POLYAMIDE PREPOLYMERS NOVARTIS AG (CH) 2006-05-26 WO disclosed
WO-2006034863-A1 PAD PRINTING METHOD FOR MAKING COLORED CONTACT LENSES NOVARTIS AG (CH) 2006-04-06 WO disclosed
US-20060065138-A1 Pad printing method for making colored contact lenses NOVARTIS AG (CH) 2006-03-30 US disclosed
WO-2006010612-A1 WATER-BASED INKS FOR HYDROGEL LENSES NOVARTIS AG (CH) 2006-02-02 WO disclosed
WO-2005054325-A2 CROSSLINKABLE POLYUREA PREPOLYMERS NOVARTIS AG (CH) 2005-06-16 WO disclosed
US-20050113549-A1 Crosslinkable polyurea prepolymers ALCON INC. (CH) 2005-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170307780-A1 OPHTHALMIC DEVICES FOR SUSTAINED DELIVERY OF ACTIVE COMPOUNDS PDE6H, PDE6C, PDE6D KDM4E 1533/4885CA12 1878/4885CA2 509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.