Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.84 |
| ▸ | JAK3 | P52333 | 12/20 | 0.84 |
| ▸ | LCK | P06239 | 8/20 | 0.84 |
| ▸ | EGFR | P00533 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16763861 | 0.91 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16764253 | 0.91 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16763849 | 0.91 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16764079 | 0.91 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL20867971 | 0.87 | BTK (0.78) | BTKJAK3LCKEGFR | |
| SCHEMBL16798429 | 0.86 | BTK (0.76) | BTKJAK3LCKEGFR | |
| SCHEMBL16763479 | 0.86 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16763759 | 0.86 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL16798483 | 0.86 | BTK (1.00) | BTKJAK3LCKEGFR | |
| SCHEMBL17883325 | 0.86 | BTK (1.00) | BTKJAK3LCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015084998-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS, INC. (US) | 2015-06-11 | — | — | WO | disclosed |