⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129989 | 0.72 | — | — | |
| SCHEMBL8772703 | 0.69 | — | — | |
| SCHEMBL28078662 | 0.68 | KDM4E (0.32) | — | |
| SCHEMBL644310 | 0.67 | — | — | |
| SCHEMBL27910344 | 0.67 | TP53 (0.53) | — | |
| SCHEMBL559604 | 0.67 | TP53 (0.38) | — | |
| SCHEMBL27521378 | 0.67 | TP53 (0.33) | — | |
| SCHEMBL4623792 | 0.65 | PIM1 (0.41) | — | |
| SCHEMBL7647881 | 0.65 | — | — | |
| SCHEMBL2815624 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213395-B | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114213395-A | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-03-22 | — | — | CN | claimed |
| CN-112759533-A | Method for generating nitrile by catalyzing amine oxidation through nonmetal mesoporous nitrogen-doped carbon material | 中国科学院大连化学物理研究所 | 2021-05-07 | — | — | CN | claimed |
| EP-3797430-A1 | DIELECTRIC FLUIDS COMPRISING NATURAL BIO-SOURCED OIL WITH INCREASED STABILITY | Cargill, Incorporated (US) | 2021-03-31 | — | — | EP | claimed |
| EP-3510404-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | Pharmakea, Inc. (US) | 2019-07-17 | — | — | EP | claimed |
| US-20190192697-A1 | CHEMICAL PROBES OF LYSYL OXIDASK-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. | 2019-06-27 | — | — | US | claimed |
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | claimed |
| CN-106905375-A | A kind of iron complex and its production and use | 上海电气电站环保工程有限公司 | 2017-06-30 | — | — | CN | claimed |
| EP-1663997-B1 | 1H-AZOLYL-METHYL-AMIDES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS NITRIFICATION INHIBITORS | PIESTERITZ STICKSTOFF (DE) | 2012-11-21 | — | — | EP | claimed |
| US-7462604-B2 | Hair growth promotor composition | LION CORPORATION (JP) | 2008-12-09 | — | — | US | claimed |
| US-20070116657-A1 | Hair growth promotor composition | LION CORPORATION (JP) | 2007-05-24 | — | — | US | claimed |
| EP-1671616-A1 | HAIR TONIC COMPOSITION | Lion Corporation (JP) | 2006-06-21 | — | — | EP | claimed |
| EP-1663997-A1 | 1H-AZOLYL-METHYL-AMIDES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS NITRIFICATION INHIBITORS | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2006-06-07 | — | — | EP | claimed |
| WO-2005035509-A1 | 1H-AZOLYL-METHYL-AMIDES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS NITRIFICATION INHIBITORS | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2005-04-21 | — | — | WO | claimed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | claimed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | claimed |
| US-12023323-B2 | Carbohydrate-binding small molecules with antiviral activity | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2024-07-02 | — | — | US | disclosed |
| CN-114213395-B | Pyrimidone acyl piperazine compound and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |
| US-4013670-A | ANTIARRHYTHMICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |
| US-4005209-A | Antiarrhythmic method utilizing fluoroalkoxy-N-piperidyl and pyridyl benzamides | RIKER LABORATORIES, INC. (US) | 1977-01-25 | — | — | US | disclosed |