Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015569 | 1.00 | KMT2A (0.50) | KMT2AHRH4DRD2DRD4DRD3 | |
| SCHEMBL1593290 | 0.98 | KMT2A (0.47) | KMT2AHRH4DRD2DRD4DRD3 | |
| Ammonia Solution, Strong SCHEMBL3939167 | 0.96 | KMT2A (0.46) | KMT2AHRH4DRD2DRD4DRD3 | |
| SCHEMBL234785 | 0.94 | KMT2A (0.44) | KMT2AHRH4DRD2DRD4DRD3 | |
| SCHEMBL170833 | 0.90 | — | — | |
| SCHEMBL16664269 | 0.82 | HRH4 (0.51) | KMT2AHRH4HRH3POLBMAPT | |
| SCHEMBL25261249 | 0.81 | KMT2A (0.34) | KMT2AHRH4DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL16648497 | 0.81 | HRH4 (0.50) | KMT2AHRH4HRH3NPC1RAB9A | |
| SCHEMBL25261248 | 0.81 | KMT2A (0.34) | KMT2AHRH4DRD2DRD4DRD3 | |
| SCHEMBL1988296 | 0.81 | KDM5B (0.37) | KMT2AHRH4DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015087995-A1 | CYCLOALKYL OR HETEROCYCLYL PYRAZOLOPYRIDINE DERIVATIVE | 第一三共株式会社 | 2015-06-18 | — | — | WO | disclosed |