SCHEMBL16804326

SCHEMBL16804326

CCO[Si](CCCOS(=O)(=O)O)(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
CA1 P00915 10/20 0.32
CA2 P00918 10/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MMP9 P14780 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CA9 Q16790 8/20 0.31
CA12 O43570 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31
CA5B Q9Y2D0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1667025 0.84 TSHR (0.34) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL23456673 0.82 CA1 (0.33) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL27603973 0.82
SCHEMBL333709 0.81 TSHR (0.34) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL27537952 0.81 CA1 (0.32) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL14658855 0.80 FNTA (0.39) FNTAFNTBCA1CA2KDM4E
SCHEMBL7094220 0.79 KDM4E (0.35) CA1CA2KDM4EUSP2ALDH1A1
SCHEMBL5265415 0.77
SCHEMBL991537 0.76 APP (0.38) LMNA
SCHEMBL29290534 0.75 FNTA (0.41) FNTAFNTBCA1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9329479-B2 Lithographic printing plate precusor AGFA GRAPHICS NV (BE) 2016-05-03 US disclosed
US-20150168837-A1 LITHOGRAPHIC PRINTING PLATE PRECUSOR ECO3 BV (BE) 2015-06-18 US disclosed