⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572890 | 0.72 | — | — | |
| SCHEMBL126608 | 0.71 | — | — | |
| SCHEMBL29930619 | 0.71 | — | — | |
| SCHEMBL28170742 | 0.71 | — | — | |
| SCHEMBL30629015 | 0.71 | — | — | |
| SCHEMBL218031 | 0.70 | — | — | |
| SCHEMBL15847948 | 0.70 | — | — | |
| SCHEMBL9572887 | 0.70 | — | — | |
| SCHEMBL1680272 | 0.70 | — | — | |
| SCHEMBL6541998 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131440-A1 | GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2020-06-25 | — | — | WO | disclosed |
| US-20200199481-A1 | GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS | EXXONMOBIL RES & ENG CO (US) | 2020-06-25 | — | — | US | disclosed |
| EP-1840399-B1 | COLLAPSIBLE COLUMN | NSK LTD (JP) | 2014-06-18 | — | — | EP | disclosed |
| EP-1889836-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (3) | EISAI R&D MAN CO LTD (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-8288538-B2 | Pyridine derivatives and pyrimidine derivatives (3) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120232049-A1 | PYRIDINE OR PYRIMIDINE DERIVATIVE HAVING EXCELLENT CELL GROWTH INHIBITION EFFECT AND EXCELLENT ANTI-TUMOR EFFECT ON CELL STRAIN HAVING AMPLIFICATION OF HGFR GENE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-7998948-B2 | Pharmaceutical composition for treating esophageal cancer | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | NAKAMOTO KAZUTAKA | 2011-08-11 | — | — | US | disclosed |
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-7855290-B2 | N-[4-({2-[({4-[2-(Dimethylamino)ethyl]piperazin-1-yl}carbonyl)amino]pyridin-4-yl}oxy)-2-fluorophenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide; hepatocyte growth factor receptor (HGFR) inhibitors; antitumor, -carcinogenic, -metastasis agents | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1782811-A1 | NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1719763-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| EP-1719762-A1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | Eisai Co., Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| EP-1669348-A1 | NOVEL ANTIFUNGAL AGENT COMPRISING HETEROCYCLIC COMPOUND | Eisai Co., Ltd. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-20060073989-A1 | Grease compostion for automobile electrical equipment auxiliary device and prelubricated rolling using the grease composition | NSK LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
| CN-1723270-A | Grease composition for automobile electrical equipment auxiliary device and prelubricated rolling bearing using the grease composition | NSK LTD (JP) | 2006-01-18 | — | — | CN | disclosed |
| US-20050277652-A1 | Novel pyridine derivative and pyrimidine derivative | EISAI CO., LTD. (JP) | 2005-12-15 | — | — | US | disclosed |
| US-6919301-B2 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20030176298-A1 | Grease composition and rolling apparatus | NSK LTD. (JP) | 2003-09-18 | — | — | US | disclosed |