Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 12/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 12/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 12/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806789 | 0.88 | HDAC1 (0.78) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL13949851 | 0.87 | HDAC1 (0.79) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806731 | 0.86 | HDAC1 (0.78) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806763 | 0.84 | HDAC3 (0.51) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806648 | 0.81 | HDAC1 (0.76) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806678 | 0.80 | HDAC6 (0.51) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806627 | 0.80 | HDAC6 (0.51) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806798 | 0.80 | HDAC2 (0.58) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL16806725 | 0.80 | HDAC3 (0.53) | HDAC1KCNH2HDAC6HDAC2HDAC3 | |
| SCHEMBL20103727 | 0.77 | BCHE (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015085860-A1 | HETEROCYCLIC HYDROXAMIC ACID COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 广州康缔安生物科技有限公司 | 2015-06-18 | — | — | WO | disclosed |