Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.56 |
| ▸ | TET3 | O43151 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.55 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.55 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806938 | 0.99 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806646 | 0.92 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806923 | 0.91 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806852 | 0.90 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806888 | 0.88 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806886 | 0.88 | HDAC1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806840 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806642 | 0.87 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806855 | 0.86 | HDAC1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16806859 | 0.86 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015085860-A1 | HETEROCYCLIC HYDROXAMIC ACID COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 广州康缔安生物科技有限公司 | 2015-06-18 | — | — | WO | disclosed |