SCHEMBL16806880 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	HDAC1	Q13547	16/20	0.72

▸	HDAC3	O15379	11/20	0.72

▸	HDAC6	Q9UBN7	11/20	0.72

▸	HDAC8	Q9BY41	10/20	0.72

▸	HDAC2	Q92769	10/20	0.72

▸	HDAC4	P56524	9/20	0.72

▸	HDAC7	Q8WUI4	9/20	0.72

▸	HDAC10	Q969S8	9/20	0.72

▸	HDAC11	Q96DB2	9/20	0.72

▸	HDAC9	Q9UKV0	9/20	0.72

▸	HDAC5	Q9UQL6	9/20	0.72

▸	KCNH2	Q12809	4/20	0.55

▸	CYP3A4	P08684	1/20	0.55

▸	NAMPT	P43490	1/20	0.41

▸	GSK3B	P49841	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16806846	0.92	HDAC1 (0.61)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806841	0.89	HDAC1 (0.59)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806848	0.88	HDAC1 (0.59)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806957	0.86	HDAC1 (0.65)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806904	0.84	HDAC1 (0.61)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL8235575	0.84	HDAC1 (1.00)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806934	0.83	HDAC1 (0.64)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806900	0.83	HDAC1 (0.59)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806843	0.83	HDAC1 (0.59)	HDAC1HDAC3HDAC6HDAC8HDAC2
SCHEMBL16806839	0.82	HDAC1 (0.58)	HDAC1HDAC3HDAC6HDAC8HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2015085860-A1	HETEROCYCLIC HYDROXAMIC ACID COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF	广州康缔安生物科技有限公司	2015-06-18	—	—	WO	disclosed