Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806887 | 0.89 | HDAC1 (0.54) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806688 | 0.85 | HDAC1 (0.58) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806857 | 0.84 | HDAC1 (0.52) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806868 | 0.84 | HDAC1 (0.47) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806910 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806895 | 0.82 | HDAC1 (0.48) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806881 | 0.82 | HDAC1 (0.55) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16807380 | 0.81 | HDAC1 (0.59) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16807375 | 0.78 | HDAC1 (0.63) | HDAC1HDAC2HDAC8HDAC6HDAC3 | |
| SCHEMBL16806866 | 0.78 | HDAC1 (0.57) | HDAC1HDAC2HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015085860-A1 | HETEROCYCLIC HYDROXAMIC ACID COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 广州康缔安生物科技有限公司 | 2015-06-18 | — | — | WO | disclosed |