Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807225 | 0.93 | HDAC6 (0.53) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806641 | 0.85 | HDAC1 (0.66) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806627 | 0.81 | HDAC6 (0.51) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806766 | 0.81 | HDAC6 (0.51) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806798 | 0.80 | HDAC2 (0.58) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806800 | 0.80 | HDAC3 (0.53) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806795 | 0.79 | HDAC1 (0.62) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806645 | 0.78 | HDAC1 (0.62) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806935 | 0.78 | HDAC6 (0.53) | HDAC6HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL16806725 | 0.78 | HDAC3 (0.53) | HDAC6HDAC3HDAC1HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015085860-A1 | HETEROCYCLIC HYDROXAMIC ACID COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 广州康缔安生物科技有限公司 | 2015-06-18 | — | — | WO | disclosed |