Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807134 | 0.96 | RARB (0.44) | RARBFFAR4FFAR1IGF1RALOX15 | |
| SCHEMBL16807126 | 0.94 | RARB (0.46) | RARBFFAR4FFAR1IGF1RALOX15 | |
| SCHEMBL16807072 | 0.93 | BACE1 (0.43) | RARBFFAR4FFAR1IGF1RALOX15 | |
| SCHEMBL16807094 | 0.91 | BACE1 (0.42) | RARBFFAR4FFAR1IGF1RALOX15 | |
| SCHEMBL16807143 | 0.91 | CYP4A11 (0.44) | RARBCYP4A11RARARARG | |
| SCHEMBL16807129 | 0.91 | FFAR1 (0.43) | RARBFFAR4FFAR1BACE1CYP4A11 | |
| SCHEMBL16807148 | 0.90 | RARB (0.50) | RARBRARARARG | |
| SCHEMBL16807142 | 0.90 | MCL1 (0.46) | RARBCYP4A11RARARARG | |
| SCHEMBL16807151 | 0.88 | RARB (0.51) | RARBRARARARGKDM4E | |
| SCHEMBL16807070 | 0.88 | IGF1R (0.44) | RARBFFAR4FFAR1IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |