SCHEMBL168075

SCHEMBL168075

CCCC(C)[CH]C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277332 0.77
SCHEMBL5931925 0.72
SCHEMBL7284358 0.72
SCHEMBL4269676 0.69 TSHR (0.38)
SCHEMBL16167304 0.69 TSHR (0.38)
SCHEMBL16167303 0.69 TSHR (0.38)
SCHEMBL38508 0.67
SCHEMBL2120839 0.67
SCHEMBL1856831 0.67
SCHEMBL2120842 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239832-A1 A PROCESS FOR THE PREPARATION OF N4-HYDROXYCYTIDINE AND ITS DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2024-07-18 US claimed
US-20240165143-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY 2024-05-23 US claimed
WO-2023086557-A1 NUCLEOSIDES FOR THE TREATMENT OF DNA VIRUS INFECTIONS EMORY UNIVERSITY (US) 2023-05-19 WO claimed
WO-2023044104-A1 PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS EMORY UNIVERSITY (US) 2023-03-23 WO claimed
WO-2022174179-A9 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2023-02-02 WO claimed
CN-115666587-A N4-hydroxycytidine and derivatives and related antiviral uses thereof 埃默里大学 2023-01-31 CN claimed
WO-2022174194-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2022-08-18 WO claimed
EP-4040965-A2 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2022-08-17 EP claimed
CN-114867351-A 4' -halo-containing nucleotide and nucleoside therapeutic compositions and uses related thereto 埃默里大学 2022-08-05 CN claimed
EP-4017501-A1 N4-HYDROXYCYTIDINE AND DERIVATIVES AND ANTI-VIRAL USES RELATED THERETO Emory University (US) 2022-06-29 EP claimed
US-20110123624-A1 FORMULATIONS COMPRISING AMINOSTEROLS ENTERIN, INC. 2011-05-26 US claimed
WO-2011056650-A2 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS ZASLOFF MICHAEL (US) 2011-05-12 WO claimed
US-20110097303-A1 METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS ENTERIN, INC. 2011-04-28 US claimed
EP-0831852-B1 NUCLEOSIDES WITH ANTI-HEPATITIS B VIRUS ACTIVITY UNIV EMORY (US) 2006-11-29 EP claimed
US-20050256034-A1 Dioxolane analogs for improved inter-cellular delivery ATTARDO GIORGIO 2005-11-17 US claimed
EP-1324997-A2 DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY Shire Biochem Inc. (CA) 2003-07-09 EP claimed
US-20030013660-A1 Dioxolane analogs for improved inter-cellular delivery SHIRE BIOCHEM INC. (CA) 2003-01-16 US claimed
US-20020061896-A1 Imidazopyrimidine nucleoside analogues with anti-HIV activity BIOCHEM PHARMA, INC. (CA) 2002-05-23 US claimed
WO-2002030922-A2 DIOXOLANE ANALOGS FOR IMPROVED INTER-CELLULAR DELIVERY SHIRE BIOCHEM INC. (CA) 2002-04-18 WO claimed
WO-2001049700-A1 IMIDAZOPYRIMIDINE NUCLEOSIDE ANALOGUES WITH ANTI-HIV ACTIVITY BIOCHEM PHARMA INC. (CA) 2001-07-12 WO claimed