Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 18/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320071 | 0.82 | SUV39H2 (0.46) | SUV39H2FFAR1 | |
| SCHEMBL16003620 | 0.81 | FFAR1 (0.47) | SUV39H2FFAR1 | |
| SCHEMBL16003628 | 0.80 | SUV39H2 (0.52) | SUV39H2FFAR1 | |
| SCHEMBL16003621 | 0.77 | SUV39H2 (0.51) | SUV39H2FFAR1TLR9TLR7 | |
| Hydrochloric Acid SCHEMBL16320532 | 0.76 | SUV39H2 (0.51) | SUV39H2FFAR1TLR9TLR7 | |
| SCHEMBL16003643 | 0.75 | FFAR1 (0.48) | SUV39H2FFAR1TLR9TLR7 | |
| SCHEMBL28338230 | 0.74 | FFAR1 (0.47) | SUV39H2FFAR1TLR9TLR7 | |
| SCHEMBL16320567 | 0.71 | FFAR1 (0.45) | SUV39H2FFAR1TLR9TLR7 | |
| SCHEMBL31091930 | 0.70 | SUV39H2 (0.43) | SUV39H2FFAR1 | |
| SCHEMBL1691855 | 0.69 | FFAR1 (0.42) | SUV39H2FFAR1TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453015-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166536-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | SUV39H2 2386/4885FFAR1 1577/4885TLR9 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.