Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.82 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793954 | 0.90 | BTK (0.80) | BTKAAK1EPHX2 | |
| SCHEMBL20461110 | 0.83 | BTK (0.83) | BTKAAK1 | |
| SCHEMBL29676735 | 0.83 | BTK (0.71) | BTK | |
| SCHEMBL16794129 | 0.83 | BTK (0.71) | BTK | |
| SCHEMBL20053938 | 0.83 | BTK (0.71) | BTKAAK1 | |
| SCHEMBL16794259 | 0.83 | BTK (0.75) | BTK | |
| SCHEMBL20054005 | 0.83 | BTK (0.68) | BTK | |
| SCHEMBL16793826 | 0.83 | BTK (0.71) | BTK | |
| SCHEMBL29676560 | 0.83 | BTK (0.75) | BTK | |
| SCHEMBL16794272 | 0.82 | BTK (0.74) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089337-A1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN IDEC MA INC. (US) | 2015-06-18 | — | — | WO | disclosed |