Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19597627 | 0.94 | PDK2 (0.41) | PDK2APPFNTAFNTBRARB | |
| SCHEMBL23561439 | 0.93 | PDK2 (0.43) | PDK2APPFNTAFNTBRARB | |
| SCHEMBL31245655 | 0.92 | PDK2 (0.40) | PDK2APPRARBRARGRXRA | |
| SCHEMBL24969712 | 0.90 | PDK2 (0.42) | PDK2APPRARBRARGRXRA | |
| SCHEMBL30318845 | 0.89 | PDK2 (0.43) | PDK2APPMEN1ALDH1A1AR | |
| SCHEMBL17194808 | 0.89 | PDK2 (0.43) | PDK2APPMEN1ALDH1A1AR | |
| SCHEMBL24968672 | 0.88 | EPHX2 (0.37) | PDK2APPRARBRARGRXRA | |
| SCHEMBL22001167 | 0.88 | PDK2 (0.37) | PDK2APPRARBRARGRXRA | |
| SCHEMBL31245649 | 0.88 | PDK2 (0.45) | PDK2APPRARBRARGRXRA | |
| SCHEMBL19797541 | 0.88 | PDK2 (0.42) | PDK2APPFNTAFNTBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11997922-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-06 | — | — | US | disclosed |
| US-11641775-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2023-05-02 | — | — | US | disclosed |
| US-20210151682-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| US-10944058-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2021-03-09 | — | — | US | disclosed |
| US-20180097178-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | US | disclosed |
| US-9882142-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20150179940-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10944058-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-20230217811-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-20210151682-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-11641775-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-20180097178-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-20150179940-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
| US-11997922-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885APP 1223/4885FNTA 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.