Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682283 | 0.91 | CXCR4 (0.51) | CXCR4HTR2AOPRM1HTR2CEP300 | |
| SCHEMBL1682296 | 0.91 | HTR2A (0.53) | CXCR4HTR2AOPRM1HTR2CEP300 | |
| SCHEMBL1682262 | 0.90 | CXCR4 (0.51) | CXCR4OPRM1TAS2R14ALDH1A1CNR1 | |
| SCHEMBL1682317 | 0.88 | CHRM4 (0.50) | CXCR4HTR2AOPRM1HTR2CCHRM2 | |
| SCHEMBL1682312 | 0.88 | HTT (0.54) | CXCR4ALDH1A1CHRM2CHRM3 | |
| SCHEMBL1682260 | 0.87 | CXCR4 (0.48) | CXCR4HTR2AOPRM1HTR2CEP300 | |
| SCHEMBL1682268 | 0.87 | USP2 (0.55) | CXCR4HTR2AALDH1A1KDM4EUSP2 | |
| SCHEMBL1682284 | 0.87 | CNR2 (0.52) | CXCR4HTR2AOPRM1HTR2CALDH1A1 | |
| SCHEMBL1682321 | 0.87 | KCNA5 (0.58) | CXCR4EP300HIF1AALDH1A1KDM4E | |
| SCHEMBL1682329 | 0.87 | CXCR4 (0.48) | CXCR4HTR2AOPRM1HTR2CEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | claimed |
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | disclosed |