Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3629001 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27306298 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL28233000 | 0.88 | — | — | |
| Bicarbonate SCHEMBL28307089 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL28234351 | 0.88 | — | — | |
| Bicarbonate SCHEMBL25372586 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL28196397 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL28096152 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL10865888 | 0.88 | — | — | |
| Bicarbonate SCHEMBL10386542 | 0.87 | CA1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116445142-A | High-temperature profile control agent for heavy oil reservoir development and preparation method and application thereof | 深圳海程油田技术服务有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-2488164-B1 | RELEASE OF AGENTS FROM CELLS | BRIGHAM & WOMENS HOSPITAL INC (US) | 2021-01-20 | — | — | EP | disclosed |
| US-9884129-B2 | Release of agents from cells | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150125540-A1 | RELEASE OF AGENTS FROM CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-07 | — | — | US | disclosed |
| US-8956863-B2 | Agents from cells | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-20120263765-A1 | AGENTS FROM CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| EP-2488164-A2 | RELEASE OF AGENTS FROM CELLS | The Brigham and Women's Hospital, Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011047277-A2 | RELEASE OF AGENTS FROM CELLS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| WO-2007022348-A2 | AMPLIFICATION OF CELL POLULATIONS FROM EMBRYONIC STEM CELLS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070042491-A1 | Amplification of cell populations from embryonic stem cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-02-22 | — | — | US | disclosed |
| US-4729886-A | GELATION INHIBITION | VIRGINIA CHEMICALS, INC. (US) | 1988-03-08 | — | — | US | disclosed |