Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 7/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065778 | 0.87 | MAOB (0.43) | NPC1GHSRMAOBRAB9A | |
| SCHEMBL15066426 | 0.86 | NPC1 (0.58) | NPC1ATMTLR9TDP1ERAP1 | |
| SCHEMBL15066288 | 0.84 | ALK (0.46) | NPC1ATMMAOBMAPTRAB9A | |
| SCHEMBL15067156 | 0.83 | NPC1 (0.61) | NPC1ATMTLR9TDP1ERAP1 | |
| SCHEMBL15067260 | 0.82 | MAOB (0.41) | NPC1ATMGHSRMAOBMAPT | |
| SCHEMBL15066137 | 0.82 | MAOB (0.41) | NPC1ATMGHSRMAOBMAPT | |
| SCHEMBL15066761 | 0.81 | NPC1 (0.56) | NPC1ATMTLR9TDP1ERAP1 | |
| SCHEMBL15067015 | 0.81 | NPC1 (0.56) | NPC1ATMTLR9TDP1ERAP1 | |
| SCHEMBL21301374 | 0.79 | NPC1 (0.48) | NPC1ATMTLR9TDP1ERAP1 | |
| SCHEMBL15065920 | 0.79 | NPC1 (0.48) | NPC1ATMTLR9TDP1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095449-A1 | METHODS FOR MODULATING THE AMOUNT RNA TRANSCRIPTS | PTC THERAPEUTICS, INC. (US) | 2015-06-25 | — | — | WO | claimed |