Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18186791 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL16830739 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL25067302 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL23475959 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL20341078 | 0.92 | GLP1R (0.58) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL23475892 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL23475977 | 0.92 | CAPN1 (0.50) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL16853275 | 0.92 | GLP1R (0.58) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL19820011 | 0.91 | CAPN1 (0.55) | GLP1RCAPN1CTSSCTSKMEN1 | |
| SCHEMBL23475929 | 0.90 | GLP1R (0.56) | GLP1RCAPN1CTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082797-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | The California Institute for Biomedical Research (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095406-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-06-25 | — | — | WO | disclosed |