SCHEMBL1683152

SCHEMBL1683152

O=C(O)c1cc(C(=O)O)cc(C(=O)O)c1.O=C(O)c1cc(C(=O)O)cc(C(=O)O)c1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1.O=C(O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
HSD17B10 Q99714 2/20 0.61
CDC25A P30304 1/20 0.61
CDC25B P30305 1/20 0.61
POLB P06746 4/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
TDP1 Q9NUW8 2/20 0.59
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.50
MYC P01106 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
PTGS2 P35354 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160655 1.00 KDM4E (0.64) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29899307 0.95 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL29350135 0.95 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23861 0.95 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL23279 0.95 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL30163040 0.95 KDM4E (0.69) KDM4EHSD17B10CDC25ACDC25BPOLB
Pyromellitic Acid SCHEMBL2489483 0.93 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
Benzene SCHEMBL9407020 0.93 KDM4E (0.73) KDM4EHSD17B10CDC25ACDC25BPOLB
Water SCHEMBL8167595 0.93 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB
SCHEMBL21328422 0.93 KDM4E (0.67) KDM4EHSD17B10CDC25ACDC25BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373406-A1 METHOD FOR PRODUCING A PROTON-CONDUCTING MEMBRANE BASF SE (DE) 2011-10-12 EP claimed
JP-4663215-B2 2011-04-06 JP claimed
WO-2011057804-A1 METHOD FOR MECHANICALLY STABILIZING NITROGEN-CONTAINING POLYMERS BASF SE (DE) 2011-05-19 WO disclosed
WO-2011054503-A1 MEMBRANE ELECTRODE ASSEMBLY AND FUEL CELLS WITH INCREASED PERFORMANCE BASF SE (DE) 2011-05-12 WO disclosed