Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 20/20 | 0.75 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.75 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.75 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4971036 | 0.94 | CSNK2A1 (0.86) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL16838029 | 0.93 | CSNK2A1 (0.88) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL29453435 | 0.86 | CSNK2A1 (1.00) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL1929492 | 0.86 | CSNK2A1 (1.00) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL30856527 | 0.86 | CSNK2A1 (1.00) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4969787 | 0.85 | CSNK2A1 (0.83) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4970775 | 0.85 | CSNK2A1 (0.88) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL10132055 | 0.81 | CSNK2A1 (0.82) | CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL2688213 | 0.81 | CSNK2A1 (0.77) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL12256473 | 0.80 | CSNK2A1 (0.79) | CSNK2A1CSNK2A2CSNK2BCSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062043-B2 | Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators | SENHWA BIOSCIENCES, INC. (TW) | 2015-06-23 | — | — | US | disclosed |