⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794394 | 0.69 | — | — | |
| SCHEMBL6282891 | 0.69 | — | — | |
| SCHEMBL9728 | 0.67 | MAPT (1.00) | — | |
| SCHEMBL17310765 | 0.67 | MAPT (0.67) | — | |
| Hydrogen Sulfide SCHEMBL3929756 | 0.64 | MAPT (0.92) | — | |
| Hydrochloric Acid SCHEMBL5548691 | 0.64 | MAPT (0.92) | — | |
| SCHEMBL135626 | 0.64 | MAPT (0.92) | — | |
| Hydrochloric Acid SCHEMBL8372850 | 0.64 | MAPT (0.92) | — | |
| SCHEMBL10000032 | 0.64 | MAPT (0.92) | — | |
| Water SCHEMBL11112402 | 0.64 | MAPT (0.92) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | claimed |
| US-20160060262-A1 | Substituted 6,6-Fused Nitrogenous Heterocyclic Compounds and Uses Thereof | GENENTECH, INC. (US) | 2016-03-03 | — | — | US | claimed |
| EP-2516441-B1 | PTERIDINONES AS INHIBITORS OF POLO-LIKE KINASE | ELAN PHARM INC (US) | 2015-01-21 | — | — | EP | claimed |
| US-20120322785-A1 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2012-12-20 | — | — | US | claimed |
| WO-2023107552-A2 | PURINES AND METHODS OF THEIR USE | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20160060262-A1 | Substituted 6,6-Fused Nitrogenous Heterocyclic Compounds and Uses Thereof | GENENTECH, INC. (US) | 2016-03-03 | — | — | US | disclosed |
| US-8623889-B2 | Substituted 6,6-fused nitrogenous heterocyclic compounds and uses thereof | GENENTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8530649-B2 | Polymer complex | THE UNIVERSITY OF TOKYO (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120322785-A1 | SUBSTITUTED 6,6-FUSED NITROGENOUS HETEROCYCLIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2012-12-20 | — | — | US | disclosed |
| US-20110098414-A1 | Polymer Complex | THE UNIVERSITY OF TOKYO (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-1630165-B1 | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | NIPPON KAYAKU KK (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7598244-B2 | [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1630165-A1 | [1,2,4 ]TRIAZOLO [1,5-A]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20050234094-A1 | Inhibition of protein kinases with piridinylimidazoles | SMITHKLINE BEECHAM P.L.C. | 2005-10-20 | — | — | US | disclosed |
| EP-1076560-A1 | INHIBITION OF PROTEIN KINASES WITH PIRIDINYLIMIDAZOLES | SMITHKLINE BEECHAM PLC (GB) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999058128-A1 | INHIBITION OF PROTEIN KINASES WITH PIRIDINYLIMIDAZOLES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-18 | — | — | WO | disclosed |
| US-4980355-A | Substituted isonicotinic acid amides; prevent attack by phytopathogenic fungi, bacteria and viruses | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |