SCHEMBL16840005

SCHEMBL16840005

CCCO[C@]1(C(=O)OC)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CNC(=O)c2ccc(-c3ccccc3)cc2)O1

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CD22 P20273 5/20 0.68
▸ SIGLEC7 Q9Y286 1/20 0.51
▸ MAG P20916 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16841340 0.94 CD22 (0.69) CD22
SCHEMBL16840014 0.94 CD22 (0.65) CD22
SCHEMBL18313784 0.91 CD22 (0.65) CD22MAG
SCHEMBL18083826 0.91 CD22 (0.76) CD22SIGLEC7
SCHEMBL18083824 0.91 CD22 (0.76) CD22SIGLEC7
SCHEMBL16362515 0.90 CD22 (0.69) CD22SIGLEC7
SCHEMBL16373000 0.89 CD22 (0.62) CD22MAG
SCHEMBL16373105 0.89 CD22 (0.62) CD22
SCHEMBL18357220 0.89 CD22 (0.62) CD22MAG
SCHEMBL16839995 0.89 CD22 (0.62) CD22MAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9539336-B2 Sialic acid derivatives BROSSMER REINHARD (DE) 2017-01-10 — — US disclosed
US-9539336-B2 Sialic acid derivatives BROSSMER REINHARD (DE) 2017-01-10 — — US disclosed
US-20150174262-A1 Sialic Acid Derivatives BROSSMER REINHARD (DE) 2015-06-25 — — US disclosed
US-20150174262-A1 Sialic Acid Derivatives BROSSMER REINHARD (DE) 2015-06-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150174262-A1 Sialic Acid Derivatives NEU1, SIGLEC9, SIGLEC7 CD22 104/4885SIGLEC7 3/4885MAG 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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