⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263974 | 0.70 | — | — | |
| SCHEMBL1763099 | 0.70 | — | — | |
| SCHEMBL9641707 | 0.67 | — | — | |
| SCHEMBL12361939 | 0.67 | — | — | |
| SCHEMBL2220875 | 0.67 | — | — | |
| SCHEMBL11804125 | 0.64 | — | — | |
| SCHEMBL10722422 | 0.64 | — | — | |
| SCHEMBL11470966 | 0.64 | — | — | |
| SCHEMBL4914424 | 0.64 | — | — | |
| SCHEMBL1567412 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016205739-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | MEKONNEN BELEW (US) | 2016-12-22 | — | — | WO | disclosed |
| WO-2015095783-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO, INC. (US) | 2015-06-25 | — | — | WO | disclosed |