Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 8/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1708351 | 0.88 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ABL1AGTR1 | |
| SCHEMBL1841659 | 0.84 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1841588 | 0.84 | — | — | |
| SCHEMBL4540031 | 0.84 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1843890 | 0.83 | ABL1 (0.45) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1842825 | 0.83 | ABL1 (0.44) | NPC1RAB9ASMN1; SMN2ABL1 | |
| Lithium Ion SCHEMBL1843158 | 0.83 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1 | |
| Lithium SCHEMBL1843160 | 0.83 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1843157 | 0.83 | ABL1 (0.43) | NPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL1842856 | 0.82 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ABL1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |