Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933326 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP9PREPDPP7 | |
| SCHEMBL31375085 | 0.88 | DPP4 (0.35) | DPP4DPP8DPP9PREP | |
| SCHEMBL20091976 | 0.85 | DPP4 (0.41) | DPP4DPP8DPP9PREPDPP7 | |
| SCHEMBL7155945 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7856069 | 0.77 | DPP4 (0.42) | DPP4DPP8 | |
| SCHEMBL2760263 | 0.74 | — | — | |
| SCHEMBL12765086 | 0.74 | — | — | |
| SCHEMBL27378731 | 0.74 | — | — | |
| SCHEMBL7857991 | 0.74 | — | — | |
| SCHEMBL26007636 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091584-A1 | THIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND THEIR USE AS TYK2 KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-06-25 | — | — | WO | disclosed |