Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684117 | 0.89 | PPARG (0.52) | PPARGMEN1KMT2AMAOBHDAC3 | |
| SCHEMBL1684191 | 0.85 | PPARG (0.52) | PPARGMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL1684119 | 0.83 | PPARG (0.51) | PPARGMAOBEPHX2 | |
| SCHEMBL2950674 | 0.82 | PPARG (0.51) | PPARGMAOB | |
| SCHEMBL2945336 | 0.81 | PPARG (0.52) | PPARGMAOB | |
| SCHEMBL1684245 | 0.79 | PPARG (0.55) | PPARGMAOBEPHX2 | |
| SCHEMBL2945150 | 0.78 | PPARG (0.47) | PPARG | |
| SCHEMBL1684268 | 0.78 | PPARG (0.48) | PPARGMAOB | |
| SCHEMBL2948358 | 0.71 | HDAC6 (0.60) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6220698 | 0.69 | PPARG (0.39) | PPARGMEN1KMT2AHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |