Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | TPI1 | P60174 | 2/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL596972 | 0.83 | TYMS (0.55) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL811703 | 0.81 | LPAR3 (0.55) | LPAR3LPAR2LPAR1BLMCSNK2A2 | |
| SCHEMBL4534560 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4531985 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4521703 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4533913 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4524705 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4528434 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4530294 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA | |
| SCHEMBL4524581 | 0.79 | LPAR3 (0.61) | LPAR3LPAR2LPAR1TYMSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654204-B1 | COLLOIDAL HYDROXIDE AQUEOUS SUSPENSION OF AT LEAST ONE TRANSITION ELEMENT SERVING TO REDUCE CHROME IN CEMENT | CHRYSO (FR) | 2009-03-04 | — | — | EP | claimed |
| WO-2015119528-A1 | INHIBITOR OF METAL CORROSION AND SCALING | РОМАНОВА, Нелли Евгеньевна | 2015-08-13 | — | — | WO | disclosed |
| WO-2011041512-A2 | COMPOSITIONS AND METHODS FOR TREATING MLV-INFECTION, AND PREVENTING AND TREATING MLV-INITIATED DISEASES | EMORY UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | GILEAD SCIENCES, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20070287644-A1 | LUBRICATING OIL COMPOSITION | SHELL OIL COMPANY | 2007-12-13 | — | — | US | disclosed |
| EP-1860175-A2 | Lubricating oil composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029939-A1 | Pre-organized tricyclic integrase inhibitor compounds | MUS81, CDKL4, INTS6 | LPAR3 2821/4885LPAR2 3445/4885LPAR1 2985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.