Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HCK | P08631 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783576 | 0.94 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| Formic Acid SCHEMBL16783472 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL16783831 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL16783887 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL16783729 | 0.90 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL16843404 | 0.89 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL16783619 | 0.89 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| SCHEMBL21327915 | 0.89 | PIK3CD (0.51) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| Formic Acid SCHEMBL16783699 | 0.89 | PIK3CD (0.46) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 | |
| Formic Acid SCHEMBL16783744 | 0.89 | PIK3CD (0.45) | PIK3CDPIK3CBPIK3CAPIK3CGABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091685-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-25 | — | — | WO | disclosed |