Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16844697 | 0.98 | GBA1 (0.37) | GBA1ALDH1A1TDP1RECQLGLA | |
| SCHEMBL16844744 | 0.95 | GBA1 (0.41) | GBA1ALDH1A1TDP1RECQLGLA | |
| SCHEMBL16844765 | 0.93 | PPP5C (0.32) | GBA1 | |
| SCHEMBL15062148 | 0.93 | GBA1 (0.44) | GBA1ALDH1A1TDP1RECQLGLA | |
| SCHEMBL16844696 | 0.92 | GBA1 (0.39) | GBA1ALDH1A1TDP1HTTMEN1 | |
| SCHEMBL15062154 | 0.91 | GBA1 (0.41) | GBA1ALDH1A1TDP1RECQLGLA | |
| SCHEMBL16844694 | 0.90 | GBA1 (0.38) | GBA1ALDH1A1TDP1HTTMEN1 | |
| SCHEMBL16844728 | 0.90 | GBA1 (0.36) | GBA1ALDH1A1TDP1 | |
| SCHEMBL20998319 | 0.90 | GBA1 (0.33) | GBA1TSHR | |
| SCHEMBL16844784 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886627-A1 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2015-06-24 | — | — | EP | disclosed |