Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.74 |
| ▸ | GAA | P10253 | 6/20 | 0.74 |
| ▸ | HTT | P42858 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | CDK2 | P24941 | 2/20 | 0.72 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.72 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.72 |
| ▸ | PIM1 | P11309 | 1/20 | 0.72 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.72 |
| ▸ | FLT4 | P35916 | 1/20 | 0.72 |
| ▸ | FLT3 | P36888 | 1/20 | 0.72 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684916 | 0.89 | MAPT (0.70) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL1684780 | 0.89 | MAPT (0.78) | MAPTALDH1A1KDM4EGAAHTT | |
| Bromide SCHEMBL18040679 | 0.88 | MAPT (0.71) | MAPTALDH1A1KDM4EGAAHTT | |
| Bromide SCHEMBL18040806 | 0.88 | MAPT (0.80) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL1684919 | 0.87 | MAPT (0.56) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL4161306 | 0.87 | SYK (0.64) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL1684694 | 0.86 | MAPT (0.78) | MAPTALDH1A1KDM4EGAAHTT | |
| Bromide SCHEMBL12541653 | 0.86 | SYK (0.63) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL1684622 | 0.86 | MAPT (0.98) | MAPTALDH1A1KDM4EGAAHTT | |
| Bromide SCHEMBL18040666 | 0.85 | MAPT (0.80) | MAPTALDH1A1KDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558612-A1 | METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119585416-A | Methods and compositions for generating endothelial cells from pluripotent stem cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-07 | — | — | CN | claimed |
| WO-2024020180-A9 | METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2025-02-06 | — | — | WO | claimed |
| CN-119185315-A | Combined pharmaceutical composition for treating octenib drug-resistant non-small cell lung cancer | 四川大学华西医院 | 2024-12-27 | — | — | CN | claimed |
| CN-117959292-A | Application of N- (4-ethoxyphenyl) -4- (2-methylimidazo [1,2-A ] pyridine-3-yl) thiazole-2-amine in preparation of antiviral drugs | 苏州大学 | 2024-05-03 | — | — | CN | claimed |
| WO-2024020180-A1 | METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-01-25 | — | — | WO | claimed |
| US-20240026301-A1 | METHODS AND COMPOSITIONS FOR GENERATING ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-01-25 | — | — | US | claimed |
| CN-116870166-A | Shh pathway for modulating biological rhythms and related applications thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-10-13 | — | — | CN | claimed |
| CN-115463218-B | Shh pathway for modulating biological rhythms and related applications thereof | 中国人民解放军军事科学院军事医学研究院 | 2023-07-14 | — | — | CN | claimed |
| EP-3825397-B1 | METHOD FOR PRODUCING PARASYMPATHETIC NEURONS | AIST (JP) | 2023-04-19 | — | — | EP | claimed |
| CN-115463218-A | Shh channel regulation and control of biological rhythm and related application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-13 | — | — | CN | claimed |
| US-11459547-B2 | Method for producing osteoblast cluster using human iPS cells | TOHOKU UNIVERSITY (JP) | 2022-10-04 | — | — | US | claimed |
| CN-114668849-A | Shh channel regulation and control of biological rhythm and related application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-06-28 | — | — | CN | claimed |
| US-11359178-B2 | Method for producing parasympathetic neurons | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2022-06-14 | — | — | US | claimed |
| US-20220145255-A1 | METHOD FOR PRODUCING OSTEOBLAST CLUSTER USING IPS CELLS | TOHOKU UNIVERSITY (JP) | 2022-05-12 | — | — | US | claimed |
| EP-2306836-B1 | BMI-1 PROTEIN EXPRESSION MODULATORS | PTC THERAPEUTICS INC (US) | 2016-09-07 | — | — | EP | claimed |
| US-8680113-B2 | BMI-1 protein expression modulators | PTC THERAPEUTICS, INC. (US) | 2014-03-25 | — | — | US | claimed |
| US-20110190239-A1 | BMI-1 PROTEIN EXPRESSION MODULATORS | PTC THERAPEUTICS, INC. (US) | 2011-08-04 | — | — | US | claimed |
| EP-2306836-A1 | BMI-1 PROTEIN EXPRESSION MODULATORS | PTC Therapeutics, Inc. (US) | 2011-04-13 | — | — | EP | claimed |
| WO-2010002985-A1 | BMI-1 PROTEIN EXPRESSION MODULATORS | PTC THERAPEUTICS, INC. (US) | 2010-01-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190239-A1 | BMI-1 PROTEIN EXPRESSION MODULATORS | BMI1, CREBBP, BAZ2A | MAPT 4026/4885ALDH1A1 2357/4885KDM4E 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.