Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930650 | 0.90 | PDE4D (0.42) | PDE4DMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL23713898 | 0.89 | STING1 (0.41) | PDE4DPDK2MAPTKMT2AKDM4E | |
| SCHEMBL20414407 | 0.87 | KMT2A (0.53) | PDE4DPDK2MAPTKMT2AKDM4E | |
| SCHEMBL802764 | 0.87 | PDK2 (0.51) | PDK2MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL29469448 | 0.87 | PDK2 (0.51) | PDK2MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL29897944 | 0.85 | PDK2 (0.52) | PDK2KMT2AKDM4EMEN1LMNA | |
| SCHEMBL28854435 | 0.85 | PDK2 (0.52) | PDK2KMT2AKDM4EMEN1LMNA | |
| SCHEMBL30177008 | 0.85 | PDK2 (0.55) | PDE4DPDK2MAPTKMT2AKDM4E | |
| SCHEMBL12781954 | 0.84 | ESR1 (0.45) | PDK2MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL30873770 | 0.83 | MAPT (0.57) | PDE4DPDK2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| EP-2875092-B1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | AFF2, ETV6, PEF1 | PDE4D 2346/4885PDK2 1521/4885MAPT 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.