Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1684099 | 0.94 | PIK3R1 (0.30) | PIK3R1PIK3CA | |
| SCHEMBL1685384 | 0.92 | — | — | |
| SCHEMBL10237722 | 0.85 | — | — | |
| SCHEMBL1682979 | 0.85 | — | — | |
| SCHEMBL1282944 | 0.85 | ABL1 (0.37) | PIK3CA | |
| SCHEMBL10235357 | 0.84 | — | — | |
| SCHEMBL1684097 | 0.84 | — | — | |
| SCHEMBL1682978 | 0.83 | GAK (0.32) | — | |
| SCHEMBL1283033 | 0.77 | RET (0.32) | PIK3R1PIK3CARET | |
| SCHEMBL1282716 | 0.77 | ABL1 (0.37) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |