Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 20/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.55 |
| ▸ | EIF4E | P06730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854170 | 0.94 | MKNK2 (0.51) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854164 | 0.92 | MKNK2 (0.49) | MKNK2MKNK1EIF4E | |
| SCHEMBL16853998 | 0.92 | MKNK2 (0.51) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854016 | 0.89 | MKNK2 (0.53) | MKNK2MKNK1EIF4E | |
| SCHEMBL16853997 | 0.89 | MKNK2 (0.55) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854169 | 0.87 | MKNK2 (0.51) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854065 | 0.85 | MKNK2 (0.49) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854040 | 0.85 | MKNK2 (0.44) | MKNK2MKNK1EIF4E | |
| SCHEMBL16854030 | 0.85 | MKNK2 (0.56) | MKNK2MKNK1 | |
| SCHEMBL16854175 | 0.84 | MKNK2 (0.57) | MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091156-A1 | SULFOXIMINE SUBSTITUTED PYRROLOTRIAZINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-25 | — | — | WO | disclosed |