Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 20/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854030 | 0.94 | MKNK2 (0.56) | MKNK2MKNK1 | |
| SCHEMBL16854025 | 0.94 | MKNK2 (0.53) | MKNK2MKNK1 | |
| SCHEMBL16854033 | 0.94 | MKNK2 (0.51) | MKNK2MKNK1 | |
| SCHEMBL16854168 | 0.93 | MKNK2 (0.50) | MKNK2MKNK1 | |
| SCHEMBL16854076 | 0.91 | MKNK2 (0.51) | MKNK2MKNK1 | |
| SCHEMBL16854072 | 0.90 | MKNK2 (0.54) | MKNK2MKNK1 | |
| SCHEMBL16854032 | 0.90 | MKNK2 (0.51) | MKNK2MKNK1 | |
| SCHEMBL16854029 | 0.88 | MKNK2 (0.52) | MKNK2MKNK1 | |
| SCHEMBL16854175 | 0.88 | MKNK2 (0.57) | MKNK2MKNK1 | |
| SCHEMBL16854165 | 0.88 | MKNK2 (0.52) | MKNK2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091156-A1 | SULFOXIMINE SUBSTITUTED PYRROLOTRIAZINES FOR PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-25 | — | — | WO | disclosed |