Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16826754 | 0.90 | LPAR1 (0.34) | CYP3A4TLR2DNM1LPAR1LPAR3 | |
| SCHEMBL19225042 | 0.88 | LPAR1 (0.35) | LPAR1LPAR3 | |
| SCHEMBL17642246 | 0.88 | LPAR1 (0.35) | LPAR1LPAR3 | |
| SCHEMBL16473879 | 0.88 | LPAR1 (0.35) | LPAR1LPAR3 | |
| SCHEMBL18289971 | 0.85 | LPAR1 (0.33) | CYP3A4TLR2DNM1LPAR1LPAR3 | |
| SCHEMBL16854578 | 0.81 | MEN1 (0.38) | LPAR1LPAR3HTT | |
| SCHEMBL26927738 | 0.81 | LPAR1 (0.44) | CYP3A4TLR2DNM1LPAR1LPAR3 | |
| SCHEMBL16473878 | 0.80 | LPAR1 (0.34) | LPAR1LPAR3 | |
| SCHEMBL26927636 | 0.79 | LPAR1 (0.50) | TLR2DNM1LPAR1LPAR3HTT | |
| SCHEMBL28278162 | 0.78 | PRKD3 (0.38) | CYP3A4LPAR1LPAR3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015092819-A2 | DERIVATIVES OF 6-(2,3-DICHLOROPHENYL)-1,2,4-TRIAZIN-5- AMINE | NEKTAR THERAPEUTICS (INDIA) PVT. LTD. (IN) | 2015-06-25 | — | — | WO | disclosed |