Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 15/20 | 0.86 |
| ▸ | SLC5A2 | P31639 | 13/20 | 0.86 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12922941 | 0.94 | SLC5A1 (0.84) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL6725644 | 0.93 | SLC5A1 (1.00) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL7581216 | 0.93 | SLC5A1 (1.00) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL30268946 | 0.93 | SLC5A1 (1.00) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL14104531 | 0.93 | SLC5A1 (1.00) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL18058596 | 0.92 | SLC5A1 (0.81) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL13678075 | 0.92 | SLC5A1 (0.81) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL15196200 | 0.92 | SLC5A1 (0.81) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL303449 | 0.92 | SLC5A1 (0.81) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 | |
| SCHEMBL16488293 | 0.92 | SLC5A1 (0.81) | SLC5A1SLC5A2HPGDHSD17B10SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236137-B1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF FATTY LIVER DISEASES | ASTELLAS PHARMA INC (JP) | 2015-06-24 | — | — | EP | disclosed |