Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121900 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL16824585 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL6504447 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL18177046 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL903505 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL12294932 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL21863336 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL20689888 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL22811006 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 | |
| SCHEMBL8749334 | 1.00 | PREP (0.68) | PREPCHRM2CHRM1CHRM3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095301-A2 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | IRM LLC (BM) | 2015-06-25 | — | — | WO | disclosed |