Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351109 | 0.84 | FFAR1 (0.51) | KDM4EALDH1A1THRBMEN1MAPT | |
| SCHEMBL4982611 | 0.83 | HSD17B10 (0.59) | HSD17B10IDO1KDM4EALDH1A1THRB | |
| SCHEMBL4345895 | 0.82 | BRD4 (0.43) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL4346825 | 0.82 | MEN1 (0.62) | KDM4EALDH1A1THRBMEN1MAPT | |
| SCHEMBL11509875 | 0.81 | MAPT (0.59) | HSD17B10IDO1KDM4EALDH1A1THRB | |
| SCHEMBL11511266 | 0.81 | HSD17B10 (0.53) | HSD17B10IDO1KDM4EALDH1A1THRB | |
| SCHEMBL4354200 | 0.81 | KMT2A (0.57) | HSD17B10KDM4EALDH1A1THRBMEN1 | |
| SCHEMBL4351131 | 0.80 | RXFP1 (0.54) | MEN1KMT2AHDAC1HDAC6HPGD | |
| SCHEMBL4355825 | 0.79 | MAPT (0.60) | KDM4EALDH1A1THRBMEN1MAPT | |
| SCHEMBL112756 | 0.79 | HSD17B10 (0.50) | HSD17B10IDO1KDM4EALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095792-A1 | CARBAMATE BENZOXAXINE PROPIONIC ACIDS AND ACID DERIVATIVES FOR MODULATION OF RORGAMMA ACTIVITY AND THE TREATMENT OF DISEASE | MERCK SHARP & DOHME CORP. (US) | 2015-06-25 | — | — | WO | disclosed |