Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783051 | 0.91 | MEN1 (0.33) | DHODHMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16783055 | 0.89 | STIM1 (0.39) | DHODHMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16783082 | 0.88 | PDE4D (0.46) | DHODHMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16783092 | 0.82 | NPC1 (0.39) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16782970 | 0.81 | PDE4D (0.46) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16783018 | 0.81 | NPC1 (0.44) | DHODHMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16782981 | 0.81 | STIM1 (0.37) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16783052 | 0.80 | PDE4D (0.42) | DHODHMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL16783012 | 0.80 | NPC1 (0.39) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16782966 | 0.79 | PDE4D (0.44) | DHODHMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015090579-A1 | PYRAZOLYL-BASED CARBOXAMIDES IV | Grünenthal GmbH (DE) | 2015-06-25 | — | — | WO | disclosed |